Hypothesis of Auto-Immune Disease Part-6 Of 8
NERVE AND BRAIN DISEASES:
DISEASES OF A MALFUNCTIONING NERVE SYSTEM:
COULD A COMBINATION OF INHIBITED CALCIUM IONS, OXYGEN DEF. LYSOSOMES, AND IRON DEFICIENCY IN THE CELLULAR METABOLISM, AND THE IRON DEF. RED NUCLEUI, BE THE DISRUPTIONS IN THE PERIPHAL NERVOUS SYSTEM THAT IS CREATING THE SYMPTOMS IN MYASTHENIA GRAVIS, PARKINSONS, ALZHEIMER'S, MS and THE HIV BREACH OF THE BLOOD BRAIN BARRIER?
If calcium ions are deficient then the chemical synapses are disrupted because there would be insufficient Ca2+ to increase and trigger the mechanism that causes the discharge of the neurotransmitters. The availability of neurotransmitters is a problem in Myasthenia Gravis, Parkinson's, and Alzheimer's to name a few …And calcium ions would be deficient with the excessive consumption of oxalic and phytic acids….So it looks to me like the deficient Ca2+ could be the cause of the deficiency in neurotransmitters transmission..
Is the LYSOSOME DISRUPTION also causing the symptoms manifested in PARKINSON'S, ALZHEIMER'S, HIV BREACHING, MULTIPLE SCLEROSIS, AND STEM CELL DESTRUCTION?:
When the lysosomes (garbage disposals) become oxygen deficient they become fragile rupture and burst. When they rupture in the brain they release nerve cell (neurons, neuroglia) destroying enzymes. The destroying enzymes can lead to the destruction of:
the stem cells/ and cells that form the blood brain barrier / that form the supporting network around neurons / that produce the myelin sheath / that generate the dopamine / that maintain the proper balance of K+ which is responsible for the generation of nerve impulses / that participate in the metabolism of neurotransmitters / that participate in brain
development / that provides the link between neurons and blood vessels / that clean up cellular debris in the Central Nervous System (CNS) / that line the ventricles of the brain and the central canal of the spinal cord / that form the cerebrospinal fluid (CSF) and assist in its circulation./ and that support neurons in the collections of neuronal cell bodies in the
peripheral nervous system ..Translated the lack of oxygen in the lysosomes release enzymes that destroy Oligodendrocytes, astrocytes, microglia, ependymal cells, neurolemmocytes (schwann cells), satellite cells (stem cells)…
In Parkinson's the dopamine producing neurons degenerate, which looks like a symptom created by the oxygen deficient garbage disposals . And then add this to deficient iron disrupting the cluster of cell bodies in the midbrain called the "Red Nucleus" which plays a major role in coordination of muscular movements. Why couldn't the nutritional disruption be playing a major role in diseases such as Parkinson's?
HIV BREACHING THE BLOOD BRAIN BARRIER:
One disruption taking place that allows this abnormality, is when the oxygen deficient garbage disposals release the destructive enzymes that destroy the nerve cells that form the blood brain barrier, thus disrupting the barriers proper functions. But another pathway is when the excessive glucose (sugar) concentration causes the endothelial cells to shrink and open up gaps at junctures that normally would be closed, when they gape open they allow abnormal substances to pass.
In Alzheimer's the networking in the brain becomes tangled, large amount of neurons or destroyed and abnormal deposits of plaque. This all looks to me like the disruption in the garbage disposals are reeking havoc.
A major symptom in MS is the destruction of the myelin sheath. This looks like the disruption in the garbage disposals, also.
THYROID AND CHOLESTEROL DISRUPTIONS:
Deficient iron inhibits the absorption of iodine, so the thyroid becomes deficient in its crucial nutrient iodine... And the virus perception by the internal system of the nutrient starved cells activates the inflammatory process. As the inflammatory response is activated histamine is released which causes the capillaries to become permeable.
This would cause excessive protein loss, including the Albumin. And a loss of albumin from the blood decreases blood's ability to suspend particles in the blood (blood colloid osmotic pressure). The colloid is the gelatinous substance produced by the thyroid gland for storing hormones. So the process of storing thyroid hormones is disrupted.
In the 2nd stage of the stress response the thyrotrophic releasing hormone (TRH) is released. TRH triggers the secretion of TSH (thyroid-stimulating hormone) which stimulates the secretion of T3 and T4 thyroid hormones. These thyroid hormones promote rapid uptake of glucose by the cells. If the storage of T3 and T4 is disrupted then the cells loss their ability to take up the glucose rapidly. The need to preserve the ATPs for the neurons become a fight or flight response and the ATP is the most important process that has to be preserved.
The 2nd stage stress response releases the hGH which inhibit the cells from taking up glucose in order to preserve the glucose in the blood for the neurons. This action would be antagonistic to the thyroid hormones. So the internal hormones are caught in the fight or flight responses and finally exhaustion the 3rd stage of the stress response takes control. And as the Thyroid hormones become depleted their functions such as stimulating the removal of cholesterol from the blood become diminished.
Plus add this to the fact that the blood capillaries have become disrupted by the inflammatory histamine and osmotic disruptions, and excessive solutes as glucose causing the nephrotic syndrome resulting in high levels of cholesterol, phospholipids, and triglycerides in the blood. And the ground work is laid for the high cholesterol levels plaguing society, all at the hands of the excess of the two acids.
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