Anti-Smoking Vaccine Effectively may Prevent Relapse in Smokers

Anti-Smoking Vaccine Effectively may Prevent Relapse in Smokers

It is hard to stop smoking, but you can do it! About 46.5 million Americans have quit smoking for good, and now there are more former smokers than current smokers. Maybe you've tried the nicotine patch or chewed nicotine gum. Maybe you've even tried the old-fashioned method and gone cold turkey, but you still keep lighting up. Quitting smoking is tough, but Anti-smoking vaccine could be another tool to help. It is estimated that about four million die each year because of cancer, heart disease and other smoking related illnesses.


Approximately half of otherwise healthy adults with invasive pneumococcal disease are cigarette smokers. Cigarette smoking is the strongest independent risk factor for invasive pneumococcal disease among immunocompetent, non elderly adults. Quitting smoking is the first and most essential step in treating COPD and slowing its progress. Many smoking cessation strategies, in fact, provide cigarette addicts with nicotine from sources other than tobacco--such as patches or gum. In many people who quit early, lung function stabilizes and eventually declines to about the same rate of nonsmokers in the same age group. In some people, lung function may even improve slightly after quitting.

Cigarette smoking causes 87 percent of lung cancer deaths. It is also responsible for many other cancers and health problems. These include lung disease, heart and blood vessel disease, stroke and cataracts. Women who smoke have a greater chance of certain pregnancy problems or having a baby die from sudden infant death syndrome (SIDS).

Scientific research review for anti-smoking vaccine:

In a study, more than twice as many people given five of the shots stopped smoking than those given fewer or phony shots, about 15 percent versus 6 percent after one year; according to American Heart Association conference. They received either four or five shots within six months. After another six months, researchers checked back with people. This development is the key for the field of smoking cessation research and could have a significant impact on how we treat patients with nicotine addiction.

About a third of smokers, or 4m people, try to quit each year, but the vast majority relapse within days or weeks and start to smoke again. The new vaccine is designed to "immunize" people who smoke against the nicotine "high." After getting the vaccine, the body produces antibodies that bind nicotine. The nicotine is prevented from leaving the blood and entering the brain. This limits the effect that nicotine has on the brain. Hopefully, without the nicotine effect, people won't enjoy smoking and will be able to quit.

"Two additional human clinical trials with other nicotine vaccines have been conducted which showed similar safety profiles and higher abstinence rates in the highest nicotine vaccine dose or antibody level groups, and we hope to conduct further trials to confirm these results; said Dorothy Hatsukami, of the University of Minnesota and lead author of the study.

Clive Bates, director of Action on Smoking and Health, said: "A nicotine vaccine would be a profound development, which would effectively become one of the most important medicines in the response to cancer, lung and heart disease. If successful, the vaccine, known as TA-NIC, will help smokers to quit by stopping nicotine from reaching the brain, thereby preventing addiction.

"This development is key for the field of smoking cessation research and could have a significant impact on how we treat patients with nicotine addiction," said Rennard, who presented his findings to a meeting of the American Heart Association in Orlando, Florida.

These findings indicate the new vaccine is effective in reducing the behavioral effects of nicotine. An appropriately designed nicotine vaccine would be beneficial to those who do not respond to conventional nicotine treatments or who cannot tolerate the side effects associated with current pharmacotherapy. The most promising clinical application of human nicotine vaccine is likely to be in relapse prevention in abstinent smokers.

The vaccine could become part of a new generation of smoking cessation treatments. They attack dependency in the brain instead of just replacing the nicotine from cigarettes in a less harmful way, like the gum, lozenges, patches and nasal sprays sold today.

You may also be interested in . . .

Comments

Post new comment

Similar

New Paperback ‘How to STOP SMOKING FOR GOOD in 5 Days’

New Paperback ‘How to STOP SMOKING FOR GOOD in 5 Days’ Winnipeg, Canada November 08, 2006. If you’re among the 70% of smokers who would love to quit smoking, if only you knew how, the new paperback, “How to STOP SMOKING FOR GOOD in 5 Days”, could be just

Analogous of Psychoactive Plant Drug Cannabis / Marijuana Might be Used for Stomach & Colon Ache

Analogous of Psychoactive Plant Drug Cannabis / Marijuana Might be Used for Stom The psychoactive drug cannabis is known by many nicknames (some pertaining to certain preparations.) It is produced from parts of the Cannabis sativa plant, primarily the cured flowers and gathered

Prescription Only Medicine(POM) / Legend Drugs / Rx-Only Drugs /Prescription Drugs-Abuse Still High

Prescription Only Medicine(Pom) / Legend Drugs / Rx-Only Drugs /Prescription Dru When prescription drugs are taken the right way, they are safe and there is little chance of addiction. Drug abuse is the use of illicit drugs or the abuse of prescription or over-the-counter drugs

Cause of Nicotine Addiction: Same Enzymatic Change Shown in Cocaine and Heroin

Cause of Nicotine Addiction: Same Enzymatic Change Shown in Cocaine And Heroin Cigarette smoking remains the leading cause of death and illness among Americans. Every year, roughly 430,000 Americans die from illnesses caused by tobacco use, accounting for one fifth of all

A Single Alcoholic Beverage Daily May Increase Breast Cancer Risk

A Single Alcoholic Beverage Daily May Increase Breast Cancer Risk Human existence is characterized by behaviour patterns—what people do to meet their biological, psychological, and social needs. These patterns may include certain ways of preparing and consuming

Smoker's Diet May Help Quit Smoking by Worsening Taste Sensory

Smoker's Diet May Help Quit Smoking by Worsening Taste Sensory The Pan American Health Organization is involved in tobacco control activities because tobacco has been defined as the number one preventable disease in the Region, causing more deaths than AIDS,

New Cause of Alcohol Dependence /Craving in Our Body

New Cause of Alcohol Dependence /Craving in Our Body Public health problems associated with alcohol consumption have reached alarming proportions, and alcohol has become one of the most important risks to health globally.In 2000 alcohol use was